Immune Modulation and Programming for Autoimmunity and Cancer Therapeutics

We aim to integrate conventional and novel immunomodulatory approaches, to develop balanced therapies for autoimmune diseases and cancer, aiming for translation.

Research

Cancer is defined by an immunosuppressive landscape that allows tumor growth and immune evasion, whereas autoimmune disorders are marked by a hyperactive immune system, leading to chronic inflammation and tissue damage. Despite their opposing immunological conditions, both diseases share regulatory pathways that present promising therapeutic targets.

At IMPACT, we aim to develop microbe based immunotherapeutic strategies to balance immune responses to overcome autoimmune diseases and cancer. By exploring the intricate interactions between the immune system and microbial metabolites, we aim to develop novel therapeutic strategies.